Proguanil Hydrochloride is the hydrochloride salt form of proguanil, a synthetic biguanide derivative of pyrimidine and an folate antagonist with antimalarial property. Upon hydrolysis, proguanil is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil selectively inhibits the bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) of plasmodium parasite, thereby disrupting deoxythymidylate synthesis and ultimately blocking DNA and protein synthesis in the parasite.
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Price:
Price 150.0 INR / Unit
Minimum Order Quantity : 25 Kilograms
Appearance : Viscous Liquid
Chemical Name : Glycerol
Molecular Formula : C3H8O3
Physical Form : Liquid
Price 25.0 INR / Kilograms
Minimum Order Quantity : 25 Kilograms
Appearance : White crystalline powder or colorless crystals
Chemical Name : Sodium Chloride
Molecular Formula : NaCl
Physical Form : Powder
Price 49000.0 INR / Vial
Minimum Order Quantity : 25 Kilograms
Appearance : Yellow crystalline powder
Chemical Name : Lornoxicam
Molecular Formula : C13H10ClN3O4S2
Physical Form : Powder
Price 14600.0 INR / Gram
Minimum Order Quantity : 25 Kilograms
Appearance : White to offwhite crystalline powder
Chemical Name : Dfructopyranose sulfamate
Molecular Formula : C12H21NO8S
Physical Form : Powder
Price 1500.0 INR/Box
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