Proguanil Hydrochloride is the hydrochloride salt form of proguanil, a synthetic biguanide derivative of pyrimidine and an folate antagonist with antimalarial property. Upon hydrolysis, proguanil is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil selectively inhibits the bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) of plasmodium parasite, thereby disrupting deoxythymidylate synthesis and ultimately blocking DNA and protein synthesis in the parasite.
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Price:
Price 500.0 INR / Strip
Minimum Order Quantity : 25 Kilograms
Molecular Formula : C21H21N HCl
Medicine Name : Cyproheptadine
Appearance : White to OffWhite Crystalline Powder
Purity(%) : 99%
Price 1500.0 INR / Gallon
Minimum Order Quantity : 25 Kilograms
Molecular Formula : C H BrClO
Medicine Name : 5Bromo2Chloro Benzoic Acid
Appearance : White to OffWhite Crystalline Powder
Purity(%) : 98% 99%
Price 25.0 INR / Kilograms
Minimum Order Quantity : 25 Kilograms
Molecular Formula : NaCl
Medicine Name : Sodium Chloride
Appearance : White crystalline powder or colorless crystals
Purity(%) : 99.5% 100%
Price 1650.0 INR / Kilograms
Minimum Order Quantity : 25 Kilograms
Molecular Formula : C6H12N2S3
Medicine Name : Monosulfiram
Appearance : White to light yellow crystalline powder
Purity(%) : 98% 99%
Price 1500.0 INR/Box
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