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Proguanil HCL

Proguanil HCL
Proguanil HCL

Proguanil HCL Specification

  • Molecular Formula
  • C11H16ClN5
  • HS Code
  • 29335990
  • EINECS No
  • 211-289-7
  • Medicine Name
  • Proguanil Hydrochloride
  • Chemical Name
  • Proguanil Hydrochloride
  • CAS No
  • 637-32-1
  • Type
  • Pharmaceutical Intermediates
  • Purity(%)
  • 98% 99%
  • Appearance
  • White or almost white crystalline powder
  • Physical Form
  • Powder
 

Proguanil HCL Trade Information

  • Minimum Order Quantity
  • 25 Kilograms
  • Delivery Time
  • 1 Week
 

About Proguanil HCL

Proguanil Hydrochloride is the hydrochloride salt form of proguanil, a synthetic biguanide derivative of pyrimidine and an folate antagonist with antimalarial property. Upon hydrolysis, proguanil is converted to its active cyclic triazine metabolite, cycloguanil, by a cytochrome P450 dependent reaction. Cycloguanil selectively inhibits the bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) of plasmodium parasite, thereby disrupting deoxythymidylate synthesis and ultimately blocking DNA and protein synthesis in the parasite.

Additional Information:

  • Delivery Time: 1 to 2 week after PO and payment
  • Packaging Details: 25 kg paking
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